Questõesde CESMAC sobre Inglês

Read the text below and answer the following question based on it.

More than half your body is not human

Human cells make up only 43% of the body's total cell count. The rest are microscopic colonists.

Understanding this hidden half of ourselves - our microbiome - is rapidly transforming understanding of diseases from allergy to Parkinson's.

No matter how well you wash, nearly every nook and cranny of your body is covered in microscopic creatures.

This includes bacteria, viruses, fungi and archaea (organisms originally misclassified as bacteria). The greatest concentration of this microscopic life is in the dark murky depths of our oxygen-deprived bowels.

The human genome - the full set of genetic instructions for a human being - is made up of 20,000 instructions called genes.

But add all the genes in our microbiome together and the figure comes out between two and 20 million microbial genes.

Prof Sarkis Mazmanian, a microbiologist from Caltech, argues: "We don't have just one genome, the genes of our microbiome present essentially a second genome which augment the activity of our own.

Science is rapidly uncovering the role the microbiome plays in digestion, regulating the immune system, protecting against disease and manufacturing vital vitamins.

It is a new way of thinking about the microbial world. To date, our relationship with microbes has largely been one of warfare.

Antibiotics and vaccines have been the weapons unleashed against the likes of smallpox, Mycobacterium tuberculosis or MRSA.

That's been a good thing and has saved large numbers of lives.

But some researchers are concerned that our assault on the bad guys has done untold damage to our "good bacteria".

Prof Knight has performed experiments on mice that were born in the most sanitised world imaginable.

He says: "We were able to show that if you take lean and obese humans and take their faeces and transplant the bacteria into mice you can make the mouse thinner or fatter depending on whose microbiome it got."

"This is pretty amazing right, but the question now is will this be translatable to humans"

This is the big hope for the field, that microbes could be a new form of medicine. It is known as using "bugs as drugs".

Adaptado de: < http://www.bbc.com/news/health-43674270> Acessado em 13 de abril de 2018.

How Sleep Strengthens Your Immune System

Numerous studies have reported the benefits of a good night’s sleep, and now researchers from Germany have found that sound sleep improves immune cells known as T cells.

“T cells are a type of… immune cells that fight against intracellular pathogens, for example virus-infected cells such as flu, HIV, herpes, and cancer cells,” Stoyan Dimitrov, PhD, told Healthline.

The study found a new mechanism through which sleep can assist the immune system.

“We show that the stress hormones adrenaline and noradrenaline and pro-inflammatory molecules prostaglandins inhibit the stickiness of a class of adhesion molecules called integrins,” Dr. Dimitrov said. “Because the levels of adrenaline, noradrenaline, and prostaglandins are low during sleep time, the stickiness of the integrins is stronger. This stickiness is important because in order for T cells to kill virus-infected cells or cancer cells, they need to get in direct contact with them, and the integrin stickiness is known to promote this contact.”

When cells in the body recognize a virally infected cell, they activate integrins, a sticky type of protein, that then allows them to attach to and kill infected cells.

The researchers compared T cells from healthy volunteers who either slept or stayed awake all night.

They found that in the study participants who slept, their T cells showed higher levels of integrin activation than in the T cells of those who were awake.

The findings indicate that sleep has the potential to improve T cell functioning. For people who get poor sleep, stress hormones may inhibit the ability of T cells to function as effectively.

Less than five hours sleep per night on a regular basis is associated with higher mortality, and having less than seven hours sleep for three nights in a row has the same effect on the body as missing one full night of sleep.

Poor sleep can increase inflammation, blood pressure, insulin resistance, cortisol, weight gain, and cardiovascular disease, as well as decrease blood sugar regulation.

Despite numerous studies proving the negative health impacts of poor sleep, experts say many people still don’t prioritize getting enough sleep.

Adaptado de: <https://www.healthline.com/health-news/how-sleepbolsters-your-immune-system#The-bottom-line> Acessado em 21 de fevereiro de 2019.

How Sleep Strengthens Your Immune System

Numerous studies have reported the benefits of a good night’s sleep, and now researchers from Germany have found that sound sleep improves immune cells known as T cells.

“T cells are a type of… immune cells that fight against intracellular pathogens, for example virus-infected cells such as flu, HIV, herpes, and cancer cells,” Stoyan Dimitrov, PhD, told Healthline.

The study found a new mechanism through which sleep can assist the immune system.

“We show that the stress hormones adrenaline and noradrenaline and pro-inflammatory molecules prostaglandins inhibit the stickiness of a class of adhesion molecules called integrins,” Dr. Dimitrov said. “Because the levels of adrenaline, noradrenaline, and prostaglandins are low during sleep time, the stickiness of the integrins is stronger. This stickiness is important because in order for T cells to kill virus-infected cells or cancer cells, they need to get in direct contact with them, and the integrin stickiness is known to promote this contact.”

When cells in the body recognize a virally infected cell, they activate integrins, a sticky type of protein, that then allows them to attach to and kill infected cells.

The researchers compared T cells from healthy volunteers who either slept or stayed awake all night.

They found that in the study participants who slept, their T cells showed higher levels of integrin activation than in the T cells of those who were awake.

The findings indicate that sleep has the potential to improve T cell functioning. For people who get poor sleep, stress hormones may inhibit the ability of T cells to function as effectively.

Less than five hours sleep per night on a regular basis is associated with higher mortality, and having less than seven hours sleep for three nights in a row has the same effect on the body as missing one full night of sleep.

Poor sleep can increase inflammation, blood pressure, insulin resistance, cortisol, weight gain, and cardiovascular disease, as well as decrease blood sugar regulation.

Despite numerous studies proving the negative health impacts of poor sleep, experts say many people still don’t prioritize getting enough sleep.

Adaptado de: <https://www.healthline.com/health-news/how-sleepbolsters-your-immune-system#The-bottom-line> Acessado em 21 de fevereiro de 2019.

How Sleep Strengthens Your Immune System

Numerous studies have reported the benefits of a good night’s sleep, and now researchers from Germany have found that sound sleep improves immune cells known as T cells.

“T cells are a type of… immune cells that fight against intracellular pathogens, for example virus-infected cells such as flu, HIV, herpes, and cancer cells,” Stoyan Dimitrov, PhD, told Healthline.

The study found a new mechanism through which sleep can assist the immune system.

“We show that the stress hormones adrenaline and noradrenaline and pro-inflammatory molecules prostaglandins inhibit the stickiness of a class of adhesion molecules called integrins,” Dr. Dimitrov said. “Because the levels of adrenaline, noradrenaline, and prostaglandins are low during sleep time, the stickiness of the integrins is stronger. This stickiness is important because in order for T cells to kill virus-infected cells or cancer cells, they need to get in direct contact with them, and the integrin stickiness is known to promote this contact.”

When cells in the body recognize a virally infected cell, they activate integrins, a sticky type of protein, that then allows them to attach to and kill infected cells.

The researchers compared T cells from healthy volunteers who either slept or stayed awake all night.

They found that in the study participants who slept, their T cells showed higher levels of integrin activation than in the T cells of those who were awake.

The findings indicate that sleep has the potential to improve T cell functioning. For people who get poor sleep, stress hormones may inhibit the ability of T cells to function as effectively.

Less than five hours sleep per night on a regular basis is associated with higher mortality, and having less than seven hours sleep for three nights in a row has the same effect on the body as missing one full night of sleep.

Poor sleep can increase inflammation, blood pressure, insulin resistance, cortisol, weight gain, and cardiovascular disease, as well as decrease blood sugar regulation.

Despite numerous studies proving the negative health impacts of poor sleep, experts say many people still don’t prioritize getting enough sleep.

Adaptado de: <https://www.healthline.com/health-news/how-sleepbolsters-your-immune-system#The-bottom-line> Acessado em 21 de fevereiro de 2019.

New Parents Don’t Get Enough Sleep for Six Years After a Child Is Born

Those first three months with a newborn can be rough, but researchers say sleep deprivation is an issue with parents for years. New parents are sometimes shocked to discover how little sleep they get in the first six months after a baby is born. They might also be discouraged to learn that their sleep patterns might not return to normal until that newborn is ready for kindergarten.

A new study published in the journal Sleep found that both parental sleep satisfaction and sleep duration sharply declined after childbirth, hitting their lowest point when a baby is 3 months old.

Women’s sleep duration and quality were far more affected than men, whether or not they breastfed their child. Women lost an average of one hour of sleep nightly compared to what they got prior to pregnancy, while men lost about 15 minutes of sleep per night.

Even four to six years after childbirth, mothers were getting 20 minutes less sleep per night than before they became pregnant, while fathers were still getting 15 minutes less sleep.

“The short-term effects of childbirth on parental sleep is well known. Our study just confirmed these effects,” Lemola told Healthline. “However, it was largely unexpected to find decreased sleep duration and sleep satisfaction six years after birth.”

Sleep was more affected among first-time parents than among parents with more than one child.

The findings were based on interviews of 4,659 parents who had a child between 2008 and 2015.

“While having children is a major source of joy for most parents, it is possible that increased demands and responsibilities associated with the role as a parent lead to shorter sleep and decreased sleep quality even up to six years after birth of the first child,” said Lemola.

Lemola said that future research would be required to determine how parents can cope with sleep loss and regain their sleep patterns sooner.

Adaptado de: <https://www.healthline.com/health-news/newparents-dont-get-sound-sleep-for-6-years#The-bottom-line> Acessado em 04 de março de 2019

New Parents Don’t Get Enough Sleep for Six Years After a Child Is Born

Those first three months with a newborn can be rough, but researchers say sleep deprivation is an issue with parents for years. New parents are sometimes shocked to discover how little sleep they get in the first six months after a baby is born. They might also be discouraged to learn that their sleep patterns might not return to normal until that newborn is ready for kindergarten.

A new study published in the journal Sleep found that both parental sleep satisfaction and sleep duration sharply declined after childbirth, hitting their lowest point when a baby is 3 months old.

Women’s sleep duration and quality were far more affected than men, whether or not they breastfed their child. Women lost an average of one hour of sleep nightly compared to what they got prior to pregnancy, while men lost about 15 minutes of sleep per night.

Even four to six years after childbirth, mothers were getting 20 minutes less sleep per night than before they became pregnant, while fathers were still getting 15 minutes less sleep.

“The short-term effects of childbirth on parental sleep is well known. Our study just confirmed these effects,” Lemola told Healthline. “However, it was largely unexpected to find decreased sleep duration and sleep satisfaction six years after birth.”

Sleep was more affected among first-time parents than among parents with more than one child.

The findings were based on interviews of 4,659 parents who had a child between 2008 and 2015.

“While having children is a major source of joy for most parents, it is possible that increased demands and responsibilities associated with the role as a parent lead to shorter sleep and decreased sleep quality even up to six years after birth of the first child,” said Lemola.

Lemola said that future research would be required to determine how parents can cope with sleep loss and regain their sleep patterns sooner.

Adaptado de: <https://www.healthline.com/health-news/newparents-dont-get-sound-sleep-for-6-years#The-bottom-line> Acessado em 04 de março de 2019

New Parents Don’t Get Enough Sleep for Six Years After a Child Is Born

Those first three months with a newborn can be rough, but researchers say sleep deprivation is an issue with parents for years. New parents are sometimes shocked to discover how little sleep they get in the first six months after a baby is born. They might also be discouraged to learn that their sleep patterns might not return to normal until that newborn is ready for kindergarten.

A new study published in the journal Sleep found that both parental sleep satisfaction and sleep duration sharply declined after childbirth, hitting their lowest point when a baby is 3 months old.

Women’s sleep duration and quality were far more affected than men, whether or not they breastfed their child. Women lost an average of one hour of sleep nightly compared to what they got prior to pregnancy, while men lost about 15 minutes of sleep per night.

Even four to six years after childbirth, mothers were getting 20 minutes less sleep per night than before they became pregnant, while fathers were still getting 15 minutes less sleep.

“The short-term effects of childbirth on parental sleep is well known. Our study just confirmed these effects,” Lemola told Healthline. “However, it was largely unexpected to find decreased sleep duration and sleep satisfaction six years after birth.”

Sleep was more affected among first-time parents than among parents with more than one child.

The findings were based on interviews of 4,659 parents who had a child between 2008 and 2015.

“While having children is a major source of joy for most parents, it is possible that increased demands and responsibilities associated with the role as a parent lead to shorter sleep and decreased sleep quality even up to six years after birth of the first child,” said Lemola.

Lemola said that future research would be required to determine how parents can cope with sleep loss and regain their sleep patterns sooner.

Adaptado de: <https://www.healthline.com/health-news/newparents-dont-get-sound-sleep-for-6-years#The-bottom-line> Acessado em 04 de março de 2019

Read the comic strip below and answer the following question based on it.