Questão 23b4d7c8-e7
Prova:
Disciplina:
Assunto:
According to the text 1, the reason why the compound phosphoethanolamine was considered as
miracle cure is:
According to the text 1, the reason why the compound phosphoethanolamine was considered as
miracle cure is:
Text 1
Brazilian courts tussle over unproven cancer treatment
Patients demand access to compound despite lack of clinical testing. A court in the Brazilian state of São Paulo has
cut off distribution of a compound that is hailed by some as a miracle cancer cure — even though it has never been
formally tested in humans. On 11 November, to the relief of many cancer researchers, a state court overturned earlier
court orders that had obliged the nation’s largest university to provide the compound to hundreds of people with
terminal cancer.
The compound, phosphoethanolamine, has been shown to kill tumor cells only in lab dishes and in mice (A. K.
Ferreira et al. Anticancer Res. 32, 95–104; 2012). Drugs that seem promising in lab and animal studies have a
notoriously high failure rate in human trials. Despite this, some chemists at the University of São Paulo’s campus in
São Carlos have manufactured the compound for years and distributed it to people with cancer. A few of those
patients have claimed remarkable recoveries, perpetuating the compound’s reputation as a miracle cure.
The Brazilian constitution guarantees universal access to health care, and it is common in Brazil for patients to turn to
the courts to access drugs that the state healthcare system does not dispense because of their cost. But
phosphoethanolamine presents a different situation because it is not really a ‘drug’ at all. It is not approved by Brazil’s
National Health Surveillance Agency.
Those who argue that people who are terminally ill have a right to try experimental medicines saw a decision in favor
of a patient in October 2015 as a significant victory. But to the university administration, drug regulators and cancer
researchers, it showed blatant disregard for the basic scientific principle that a drug should be demonstrated to be
safe and effective before being given to patients outside of a clinical trial.
Source: Nature 527, 420–421 (adapted). http://www.nature.com/news/brazilian-courts-tussleover-unproven-cancer- treatment-1.18864.
Text 1
Brazilian courts tussle over unproven cancer treatment
Patients demand access to compound despite lack of clinical testing. A court in the Brazilian state of São Paulo has
cut off distribution of a compound that is hailed by some as a miracle cancer cure — even though it has never been
formally tested in humans. On 11 November, to the relief of many cancer researchers, a state court overturned earlier
court orders that had obliged the nation’s largest university to provide the compound to hundreds of people with
terminal cancer.
The compound, phosphoethanolamine, has been shown to kill tumor cells only in lab dishes and in mice (A. K.
Ferreira et al. Anticancer Res. 32, 95–104; 2012). Drugs that seem promising in lab and animal studies have a
notoriously high failure rate in human trials. Despite this, some chemists at the University of São Paulo’s campus in
São Carlos have manufactured the compound for years and distributed it to people with cancer. A few of those
patients have claimed remarkable recoveries, perpetuating the compound’s reputation as a miracle cure.
The Brazilian constitution guarantees universal access to health care, and it is common in Brazil for patients to turn to
the courts to access drugs that the state healthcare system does not dispense because of their cost. But
phosphoethanolamine presents a different situation because it is not really a ‘drug’ at all. It is not approved by Brazil’s
National Health Surveillance Agency.
Those who argue that people who are terminally ill have a right to try experimental medicines saw a decision in favor
of a patient in October 2015 as a significant victory. But to the university administration, drug regulators and cancer
researchers, it showed blatant disregard for the basic scientific principle that a drug should be demonstrated to be
safe and effective before being given to patients outside of a clinical trial.
Source: Nature 527, 420–421 (adapted). http://www.nature.com/news/brazilian-courts-tussleover-unproven-cancer- treatment-1.18864.
A
its efficiency in curing a high percentage of patients who underwent treatment.
B
some cancer patients claimed they recovered after using phosphoethanolamine.
C
it had a notoriously high failure rate in human trials and it is not really a ‘drug’ at all.
D
university officials from São Carlos have manufactured the compound for years.
E
researchers from all over Brazil are providing the compound to people with terminal cancer.